Researched and written by Keith Bishop, Cancer Coach, Clinical Nutritionist, Retired Pharmacist

D-mannose, a simple sugar, has been studied for its potential anti-cancer actions. Below, we explore its mechanisms, effects on cancer treatments, and considerations for its use based on scientific research. Mannose cancer research is in the early stages and limited to laboratory cancer cell studies, a few animals, and even fewer human studies.

The Warburg Effect and D-Mannose

The Warburg effect is where cancer cells rely heavily on glycolysis (glucose) for energy production, even in the presence of oxygen. Research indicates that D-mannose can disrupt glycolysis, affecting the Warburg effect and reducing cancer cell proliferation. A study published in Nature Nature link shows how D-mannose interferes with glucose metabolism, impairing tumor growth.

D-Mannose's Impact on Glucose Metabolism

D-mannose alters glucose metabolism by inhibiting pathways like the pentose phosphate pathway, wh...

Researched and written by Keith Bishop, Clinical Nutritionist, Cancer Coach, and Retired Pharmacist

My wife and I come from families with histories of cancer and dementia, and I was personally diagnosed with rheumatoid arthritis. As a teenager with acne, I took powerful antibiotics for years that contributed to loose stools. As I shifted my focus from traditional pharmacy to natural health and cancer support, I uncovered the crucial role of digestive health in tackling these health challenges. Since prioritizing my gut health, I’ve experienced a significant reduction in autoimmune aches and pains and tested negative for rheumatoid arthritis, transforming my overall well-being.

The gut microbiome, a vast ecosystem of trillions of microorganisms in our digestive tract, is emerging as a key player in cancer, health, and disease. Its influence extends beyond digestion, impacting immune function, mental health, and cancer prevention and treatment. Here's how this microscopic community can...

Researched and written by Keith Bishop, Clinical Nutritionist, Cancer Coach, Retired Pharmacist

Melatonin, often called the "sleep hormone," is a naturally occurring compound produced by the pineal gland in the brain. While its primary role is to regulate the sleep-wake cycle, emerging research has revealed its potential as a potent anticancer agent. This blog explores melatonin's anticancer properties, additional health benefits, potential side effects, role in cancer treatment, recommended dosages, and possible drug interactions.

What is Melatonin?

Melatonin is a hormone that helps regulate circadian rhythms, ensuring a healthy sleep-wake cycle. It is also a potent antioxidant, capable of neutralizing free radicals and reducing oxidative stress, which are key contributors to cellular damage and aging.

Melatonin Anticancer Activity*

Research has shown that melatonin exhibits several anticancer properties:

• Inhibits Tumor Growth: Melatonin can suppress tumor growth by regulating
...

Researched and written by Keith Bishop, Clinical Nutritionist, Cancer Coach, Retired Pharmacist

Citrus fruits are celebrated for their health benefits, but did you know they might pose a hidden risk when combined with sun exposure? Recent studies have raised concerns about certain compounds in citrus fruits that could increase the risk of skin cancer. Here's what you need to know to stay safe while enjoying the sunshine.

The Cancer Culprit: Psoralens and Furocoumarins

Citrus fruits, such as oranges, lemons, limes, and grapefruits, contain naturally occurring compounds called psoralens and furocoumarins. These compounds are known as photocarcinogens, meaning they can interact with sun ultraviolet (UV) radiation to cause DNA damage in skin cells. This damage may increase the risk of developing skin cancers, including basal cell carcinoma (BCC)[i] [ii]  [iii], squamous cell carcinoma (SCC),[iv] and melanoma.[v] One population study found one serving per day of an increase in total citr...

Breaking Ground in Cancer Research: Ivermectin Cancer Potential Revealed!

Researched and written by Keith Bishop, Clinical Nutritionist, Cancer Coach, Retired Pharmacist

Notice: This information is intended for educational purposes only and should not be used as a substitute for professional medical advice, diagnosis, or treatment. Always consult with your healthcare team before considering the integration of ivermectin or any other therapy into your health program to ensure it aligns with your specific medical needs and circumstances.

Ivermectin History

Ivermectin is a medication primarily used to treat parasitic infections. It was initially developed in the 1970s for veterinary use but was later approved for human use in the 1980s. In humans, ivermectin is prescribed for conditions such as strongyloidiasis (intestinal infection caused by threadworms) and onchocerciasis (river blindness). It is also used topically to treat head lice and skin conditions like rosacea.

Ivermectin An...

Researched and written by Keith Bishop, Clinical Nutritionist, Cancer Coach, Retired Pharmacist

This blog post on toxic metals and cancer is in active research and writing. Please check back for updates. 

1. Introduction

• Brief overview of the topic
• Importance of understanding the impact of toxic metals on cancer risk

1. Toxic Metals and Their Carcinogenic Effects

• Definition of toxic metals
• Common toxic metals associated with cancer risk: Lead (Pb), Chromium (Cr), Arsenic (As), Cadmium (Cd), Nickel (Ni), Mercury (Hg)
• Mechanisms of carcinogenicity
• Common exposures

III. Types of Cancers Linked to Toxic Metals

• Lung Cancer
• Breast Cancer
• Prostate Cancer
• Gastric Cancer
• Liver Cancer
• Bladder Cancer

1. Testing for Toxic Metals

• Methods of testing: Hair, Urine, Blood
• Hair Test: Long-term exposure detection
• Urine Test: Recent exposure detection
• Blood Test: Current exposure detection
• Procedure and interpretation of results
• ZRT – blood and urine test
• Mo
...

Modified Citrus Pectin MCP and Cancer

Researched and written by Keith Bishop, Clinical Nutritionist, Cancer Coach, and Retired Pharmacist

PectaSol is a form of modified citrus pectin (MCP) derived from the pith (the white, spongy layer between the outer peel) of citrus fruits. It has been modified to a specific molecular weight and structure to ensure bioavailability and systemic benefits. PectaSol is known for inhibiting galectin-3, a protein that promotes cancer growth and metastasis and cancer.[i]

How Does PectaSol Work?

PectaSol works by blocking galectin-3, which is involved in cancer cell adhesion, proliferation, and metastasis.[ii] By inhibiting galectin-3 and galectin-8,[iii] PectaSol can help prevent cancer cells from spreading and support the effectiveness of chemotherapy, radiotherapy, and cancer treatment. MCP, given orally, inhibits carbohydrate-facilitated tumor growth, angiogenesis (new blood vessel growth), and metastasis in the body via its effects on galectin-3 fu...

Researched and written by Keith Bishop, Clinical Nutritionist, Cancer Coach, Retired Pharmacist

Quercetin, a naturally occurring flavonoid in many fruits and vegetables, has garnered significant attention for its anticancer properties.

Mechanisms of Action Against Cancer

Quercetin exerts its anticancer effects through multiple pathways. It inhibits tumor proliferation, invasion, and metastasis by modulating various signaling pathways within cancer cells. These pathways include apoptotic, p53, NF-κB, MAPK, JAK/STAT, PI3K/AKT, and Wnt/β-catenin pathways. Quercetin also regulates the activity of oncogenic and tumor suppressor ncRNAs, contributing to its anticancer properties.

Food Sources of Quercetin

Quercetin is abundant in many fruits and vegetables. Here are the top 10 foods rich in quercetin:[i]

• Onions (especially red onions)
• Apples (especially the peals)
• Berries (such as blackberries, blueberries, and cranberries)
• Kale
• Broccoli
• Spinach
• Capers
• Cherry tomatoes
• Green
...

Recent medical studies have shown promising anticancer effects, making it a potential natural treatment for cancer.

Written by Keith Bishop, Clinical Nutritionist, Cancer Coach, and Retired Pharmacist

Boswellia serrata, or frankincense, has been used in traditional medicine for centuries. Recent studies have shown promising anticancer effects, making it a potential natural treatment for cancer.

Health Benefits of Boswellia

Boswellia offers a range of health benefits beyond its anticancer properties. Its potent anti-inflammatory effects make it helpful in treating conditions such as arthritis, inflammatory bowel disease (IBD), and asthma. Additionally, Boswellia can help reduce pain and improve respiratory health.[i]

Boswellia Anticancer  Ingredients and Mechanisms

Boswellia's anticancer properties are primarily attributed to its active compounds, boswellic acids. These compounds inhibit the production of leukotrienes, molecules that contribute to inflammation and tumor gro...

Written by Keith Bishop, Clinical Nutritionist, Cancer Coach, and Retired Pharmacist

Cancer cells can remarkably manipulate their environment to support their growth and spread. One key component of this environment is collagen, a significant protein in the extracellular matrix (ECM). Collagen provides structural support and is crucial in cancer progression and metastasis.

I want to share my concerns since collagen peptide protein powders are popular. 

Collagen peptide proteins, derived from enzymatic hydrolysis of collagen, provide high doses of type I and III collagen. These collagens are particularly significant in cancer progression, as they contribute to the structural integrity and stiffness of the tumor microenvironment. Cancer cells can exploit these collagen-rich environments to enhance their adhesion, migration, and invasion capabilities, promoting tumor growth and metastasis. Studies have shown that cancer cells can utilize collagen peptides to create a protective extrace...